List of cell lines by the breast cancer

List of cell lines

Mainly based on Lacroix and Leclercq (2006). For more data on the nature of TP53 mutations in breast cancer cell lines, see Lacroix et al. (2010).

This is an incomplete list, which may never be able to satisfy particular standards for completeness. You can help by expanding it with reliably sourced entries.

Cell line	Primary tumor	Origin of cells	Estrogen receptors	Progesterone receptors	ERBB2 amplification	Mutated TP53	Tumorigenic in mice
600MPE	Invasive ductal carcinoma		+	–		–
AU565	Adenocarcinoma		–	–	+	–
BT-20	Invasive ductal carcinoma	Primary	No	No	No	Yes	Yes
BT-474	Invasive ductal carcinoma	Primary	Yes	Yes	Yes	Yes	Yes
BT-483	Invasive ductal carcinoma		+	+		–
BT-549	Invasive ductal carcinoma		–	–		+
Evsa-T	Invasive ductal carcinoma, mucin-producing, signet-ring type	Metastasis (ascites)	No	Yes	?	Yes	?
Hs578T	Carcinosarcoma	Primary	No	No	No	Yes	No
MCF-7	Invasive ductal carcinoma	Metastasis (pleural effusion)	Yes	Yes	No	No (wild-type)	Yes (with estrogen supplementation)
MDA-MB-231	Invasive ductal carcinoma	Metastasis (pleural effusion)	No	No	No	Yes	Yes
SkBr3	Invasive ductal carcinoma	Metastasis (pleural effusion)	No	No	Yes	Yes	No
T-47D	Invasive ductal carcinoma	Metastasis (pleural effusion)	Yes	Yes	No	Yes	Yes (with estrogen supplementation)